The PC-based treatment approach was originally developed by Prof. Zihl (1988, 1990) and has since been used with various modifications in 13 studies on a total of 551 patients with homonymous visual field loss and persistent visual disabilities.

The main outcome of saccadic training is a significant improvement in visual search performance accompanied by more efficient oculomotor strategies, and a reduction in visual disability as assessed by standardized questionnaires and behavioral measures. These include measures of improvements in navigation skills and object finding. The efficacy of this treatment approach to improving of visual overview and visual exploration is superior to practice with reading (Schuett et al., 2012), non-specific visual training (Roth et al., 2009), standard occupational therapy (Mödden et al., 2012) or counseling with regards to coping strategies (Zihl, 2011). Importantly, time since brain injury (Zihl, 2011) and age of hemianopic patients (Schuett & Zihl, 2012) do not play a significant role in the treatment effect.

NeuroEyeCoach Clinical Studies

  1. Use of NeuroEyeCoach to improve eye movement efficacy in patients with homonymous visual field loss
    Author: Sahraie, A., Smania, N., Zihl, J.
    Publication: BioMed Research International  http://cdn2.hubspot.net/hubfs/548508/PDFs/Use_of_NeuroEyeCoach_to_Improve_Eye_Movement_Efficacy_in_Patient_with_Homonymous_Visual_Field_Loss.pdf
  2. Visual scanning behaviour in patients with homonymous hemianopia
    Author: Zihl, J.
    Publication: Neuropsychologia, 1995, 33:287-303.
    http://www.sciencedirect.com/science/article/pii/002839329400119A
  3. Rehabilitation of Visual Disorders after brain injury
    Author: Zihl, J.
    Publication: Psychology Press, 2nd Edition, Hove (GB) and New York (USA), 2011.
    http://samples.sainsburysebooks.co.uk/9781136911545_sample_842299.pdf
  4. Guided Search 2.0, A revised model of visual search
    Author: Wolfe, J.
    Publication: Psychonomic Bulletin & Review Vol 1 (2), 1994, 202-238.
    http://search.bwh.harvard.edu/new/pubs/guidedsearch2.0.pdf
  5. Rehabilitation of homonymous scotomata in patients with postgeniculate damage of the visual system: Saccadic compensation training
    Authors: Kerkhoff, G., Münssinger, U., Haaf, E., Eberle-Strauss, G., Stögerer, E.
    Publication: Restorative Neurology and Neuroscience, 1992, 4:245-254.
    http://www.ncbi.nlm.nih.gov/pubmed/21551879
  6. Compensatory strategies following visual search training in patients with homonymous hemianopia: an eye movement study
    Authors: Mannan, S.K., Pambakian, A.L.M., Kennard, C.
    Publication: Journal of Neurology, 2010, 257:1812-1821.
    http://www.ncbi.nlm.nih.gov/pubmed/20556413
  7. Eye-movement training-induced plasticity in patients with post-stroke hemianopia
    Authors: Nelles, G., Pscherer, A., de Greiff, A., Forsting, M., Gerhard, H., Esser, J., Diener, H.C.
    Publication: Journal of Neurology, 2009,256:726-733.
    http://link.springer.com/article/10.1007%2Fs00415-009-5005-x
  8. A randomized controlled trial comparing 2 interventions for visual field loss with standard occupational therapy during inpatient stroke rehabilitation
    Authors: Mödden, C., Behrens, M., Damke, I., Eilers, N., Kastrup, A., Hildebrandt, H.
    Publication: Neurorehabilitation and Neural Repair, 2012, 26:463-469.
    http://www.ncbi.nlm.nih.gov/pubmed/22140199
  9. Rehabilitation of reading and visual exploration in visual field disorders: transfer or specificity?
    Authors: Schuett, S., Heywood, CA., Kentridge, R.W., Dauner, R., Zihl, J.
    Publication: Brain, 2012, 135:912-921.
    http://brain.oxfordjournals.org/content/135/3/912
  10. Compensatory visual field training for patients with hemianopia after stroke
    Authors: Nelles, G., Esser, J., Eckstein, A., Tiede, A., Gerhard, H., Diener, H.C.
    Publication: Neuroscience Letters, 2001, 306:189-192.
    http://www.sciencedirect.com/science/article/pii/S0304394001019073
  11. Saccadic visual search training: A treatment for patients with homonymous hemianopia
    Authors: Pambakian, A.L.M., Mannan, S.K., Hogson, T.L., Kennard, C.
    Publication: Journal of Neurology, Neurosurgery, and Psychiatry, 2004, 75:1443-1448.
    http://jnnp.bmj.com/content/75/10/1443.short
  12. Incidence of neurological vision impairments in patients who suffer from an acquired brain injury
    Author: Clarke, G.
    Publication: International Congress Series, 2005, 1282:365-369.
    http://www.sciencedirect.com/science/article/pii/S0531513105009702
  13. Changes in stroke epidemiology, prevention, and treatment
    Author: Kinley, S.
    Publication: Circulation, 2011, 124:e494-e496.
    http://circ.ahajournals.org/content/124/19/e494.extract
  14. Heart Disease and Stroke Statistics—2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    Authors: Lloyd-Jones, et al.
    Publication: Circulation, 2009, 119:e21-e181.
    http://circ.ahajournals.org/content/early/2008/12/15/CIRCULATIONAHA.108.191261.full.pdf
  15. Visual impairment after stroke: Do patients require vision assessment?
    Authors: Rowe, F., Brand, D., Jackson, C.A., Price, A., Walker, L., Harrison, S. et al.
    Publication: Age and Ageing, 2009, 38:188-193.
    http://ageing.oxfordjournals.org/content/38/2/188.full.pdf+html
  16. Does age matter? Age and rehabilitation of visual field disorders after brain injury
    Authors: Schuett, S., Zihl, J.
    Publication: Cortex, 2013, 49(4):1001-12.
    http://www.ncbi.nlm.nih.gov/pubmed/22622434
  17. The frequency of occurrence, types, and characteristics of visual field defects in acquired brain injury: A retrospective analysis.
    Authors: Suchoff, IB., Kapoor, N., Ciuffreda, K.J., Rutner, D., Han, E., Craig, S.
    Publication: Optometry, 2008, 79:259-265.
    http://www.advancedvisiontherapycenter.com/Documents%20and%20Settings/58/Site%20Documents/Studies/The%20frequency%20of%20occurrence,%20types,%20and%20characteristics%20of%20visual%20field%20defects%20in%20acquired%20brain%20injury.PDF
  18. Stroke incidence and prevalence in Europe: a review of available data
    Authors: Truelsen T., Piechowski-Jóźwiak B., Bonita, R., Mathers C., Bogousslavsky J., Boysen, G.
    Publication: European Journal of Neurology, 2006, 13:581-598.
    http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1331.2006.01138.x/full
  19. Homonymous hemianopia in stroke
    Authors: Zhang, X., Kedar, S., Lynn, M.J., Newman, N.J., Biousse, V.
    Publication: Journal of Neuro-Ophthalmology, 2006, 26:180-183.
    http://journals.lww.com/jneuro-ophthalmology/Fulltext/2006/09000/Homonymous_Hemianopia_in_Stroke.5.aspx#
  20. Sehen (engl.: Vision)
    Author: Zihl, J.
    Publication in: Neuropsychologische Rehabilitation. Grundlagen – Diagnostik – Behandlungsverfahren. Von Cramon D. & Zihl, J. (Eds)., 1988, pp. 105-131. Berlin: Springer.
  21. Treatment of patients with homonymous visual field disorders [in German]
    Author: Zihl, J.
    Publication: Zeitschrift für Neuropsychologie, 1990, 2:95-101 (no link available)
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