Research Related to NovaVision VRT™ Vision Restoration Therapy™

Read the research on NovaVision VRT Vision Restoration Therapy.

New Research Supports Vision Restoration Therapy Can Help Improve Vision in Stroke and Brain Injury Patients

A functional magnetic resonance imaging (fMRI) study performed by researchers at Columbia University Medical Center on patients who have lost vision from stroke or brain injury shows that by performing Vision Restoration Therapy (VRT) the patients had an increase in brain activity.

VRT after Brain Damage: Subjective Improvements

Taylor & Francis Healthsciences, Visual Impairment Research- 2003, Vol. 5 No. 3, pp. 157-178. Authors: Iris Mueller, Dorothe A. Poggel, Sigrid Kenkel, Erich Kasten, Bernhard A. Sabel

Editorial: Residual Vision and Plasticity after Visual System Damage

Restorative Neurology and Neuroscience 15 (1999) 73-79. Author: Bernhard A. Sabel

Increased Receptive Field Size in the Surround of Chronic Lesions in the Adult Cat Visual Cortex

Cerebal Cortex, March 1999; 9:101-109. Authors: Ulf T. Eysel and Georg Schweigart

Receptive Field Dynamics in Adult Primary Visual Cortex

Nature, Volume 356, March 12, 1992. Authors: Charles D. Gilbert and Torsten N. Wiesel

Does VRT Change Absolute Homonymous Visual Field Defects - A Fundus-Controlled Study

British Journal of Ophthalmology, 2005; 89:30-35. Authors: J Reinhard, A Schreiber, U Schiefer, E Kasten, B A Sabel, S Kenkel, R Vonthein, S Trauzettel-Klinski

Computer-Based Training of Stimulus Detection Improves Color and Simple Pattern Recognition in the Defective Field of Hemianopic Subjects

Massachussetts Institute of Technology, Journal of Cognitive Neuroscience, 2000; 12:6, pp. 1001-1012. Authors, Erich Kasten, Dorothe A. Poggel and Bernhard A. Sabel

Vision Restoration Therapy (VRT) after Brain Damage: Subjective Improvements of Activities of Daily Life (ADL) and Their Relationship to Visual Field Enlargements

A recent restrospective study shows that Vision Restoration Therapy (VRT) leads to subjective improvements of vision-guided activities in everyday life. Even patients with small visual field enlargements noted subjective improvements in daily life. Subjective benefits identified include walking/mobility, confidence/independence, reading, hobbies/watching TV.

Attentional Cueing Improves Vision Restoration Therapy in Patients With Visual Field Defects

In a retrospective, randomized clinical trial, treatment outcome was compared in patients with postgenicular visual system lesions who received either standard VRT or VRT with attentional cueing for a six-month trial period. Attentional cueing was found to amplify long-term neuronal plasticity.

Computer-Based Training for the Treatment of Partial Blindness

The results of two independent clinical trials show that, contrary to conventional wisdom, partial blindness after a brain injury is treatable. Computer-based vision training is both a cost-efficient and effective way to improve vision in patients with visual-field defects.

Restoration of Vision by Training of Residual Functions

With high-resolution diagnostic testing that identifies areas of residual vision, patients are able to restore vision lost through injury with training—and maintain the improved visual function even years after training (therapy) ends.

Stability of Visual Field Enlargements Following Computer-Based Restitution Training — Results of a Follow-up

Patients with cerebral lesions can maintain or even increase the significant visual field enlargements induced by computer training (therapy)—even two years after training is discontinued.

Unusual Spontaneous and Training-Induced Visual Field Recovery in a Patient with a Gunshot Lesion

By observing the extraordinary recovery of a patient with a gunshot wound to the head, the authors show that the systematic stimulation provided during visual restitution therapy can induce brain plasticity and functional recovery in partially damaged neuronal areas.

Simple Pattern Recognition in the Defective Field of Hemianopic Subjects

Computer-based therapy designed to increase visual field size and restore vision lost after injury also improved patients’ ability to recognize color and form.

Blindsight after Optic Nerve Injury Indicates Functionality of Spared Fibers

Patients with partial optic nerve damage show responses in “blind” regions using stimulus detection, localization and spatial summation tasks. Blindsight suggests that uninjured nerve fibers are functional.

Changes in Visual Cortex Excitability in Blind Subjects as Demonstrated by TMS

Any attempt to restore vision requires an understanding of the patient’s ability to generate conscious visual experience. Transcranial magnetic stimulation—which uses a powerful magnetic field to alter and sometimes aid brain activity— helps researchers measure residual function of the visual cortex.

Co-expression of c-Jun and ATF-2 Characterizes the Surviving Retinal Ganglion Cells Which Maintain Axonal Connections after Partial Optic Nerve Injury

Understanding the role of immediate-early genes may help in the development of treatments for central nervous system injuries. Here, researchers focus on several IEGs to determine their effect on cell death—or survival.

The Development of Visual Functions in Cerebrally Blind Children During a Systematic Visual Field Training

An article appearing in the Restorative Neurology & Neuroscience Journal by: R. Werth and M. Moehrenschlager.

Detection and Follow-up of Homonymous Visual Field Defects Perimetric Essentials for Evaluation of Spontaneous Recovery

An article appearing in the Restorative Neurology & Neuroscience Journal by U. Schiefer, M. Skalej, T.J. Dietrich and C. Braun.

Restoration of Vision I: Neurobiological Mechanisms of Restoration and Plasticity after Brain Damage — A Review

An article appearing in the Restorative Neurology & Neuroscience Journal by Bernhard A. Sabel.

Restorative and Compensatory Therapy Approaches in Cerebral Blindness — A Review

An article appearing in the Restorative Neurology & Neuroscience Journal by Georg Kerkhoff.

Variability of Residual Vision in Hemianopic Subjects

An article appearing in the Restorative Neurology & Neuroscience Journal by C. Mark Wessinger, Robert Fendrich, and Michael S. Gazzaniga.

Role of Neurotrophins in Neural Plasticity: What We Learn from the Visual Cortex

An article appearing in the Restorative Neurology & Neuroscience Journal by N. Berardi, C. Lodovichi, M. Caleo, T. Pizzorusso and L. Maffei.

On Nature and Limits of Cortical Developmental Plasticity After an Early Lesion, In a Child

An article appearing in the Restorative Neurology & Neuroscience Journal by: Giorgio M. Innocenti, Daniel C. Kiper, Maria G. Knyazeva and Thierry W. Deonna.

Numerous studies have tested the effectiveness of NovaVision VRT, a technique for treating vision loss after brain injury or stroke. The studies have revealed that VRT, which is based on the science of Neuroplasticity (the brain's ability to heal itself), produces encouraging clinical results.

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